eng URI http://hdl.handle.net/10795/3354 ιατρική φυσική πυρηνική ιατρική θεραπευτική μετρολογία The nearly tissue equivalent MRI properties and the unique ability of registering 3D dose distributions of polymer gels were exploited to assess the total geometrical accuracy in clinical Gamma Knife applications, taking into account the combined effect of the unit’s mechanical accuracy, dose delivery precision and the geometrical distortions inherent in MR images used for irradiation planning. Comparison between planned and experimental data suggests that the MR-related distortions due to susceptibility effects dominate the total clinical geometrical accuracy which was found within 1 mm. The dosimetric effect of the observed sub-millimetre uncertainties on single shot GK irradiation plans was assessed using the target percentage coverage criterion, and a considerable target dose underestimation was found. 6 pp. LOMv1.0 creator LOMv1.0 publisher LOMv1.0 Scientific Coordinator LOMv1.0 Project Executing Organisation 2011-08-31 Digital Library of the Operational Programme "Education and Lifelong Learning" abstract types Text Polymer gels Dosimetry Radiosurgery Therapeutic radiation Gamma Knife Radiosurgery system Ραδιοχειρουργική Δοσιμετρία Gel πολυμερισμού 882780 application/pdf http://repository.edulll.gr/edulll/bitstream/10795/3354/2/3354_1.90_%ce%94%ce%97%ce%9c_31_8_11.pdf URI http://hdl.handle.net/10795/3354 LOMv1.0creator 2016-05-23T12:47:05Z LOMv1.0validator 2016-05-23T12:47:05Z LOMv1.0 gre no no Copyright EYD-EPEDBM (Operational Programme "Education and Lifelong Learning")